Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. This study examined the cost-effectiveness of docetaxel in combination with doxorubicin and cyclophosphamide compared with 5-fluorouracil in combination with doxorubicin and cyclophosphamide, after primary surgery for women with operable, axillary lymph node-positive breast cancer. Docetaxel offered improved survival, compared with fluorouracil, and it provided good value for money from the perspective of the public payer.
Breast cancer is the most common form of malignancy in women, especially in those aged over 50 years. Established risk factors include age, early onset of menstruation, late menopause, older age at first completed pregnancy, and a family history of breast cancer. The use of oral contraceptives or hormone replacement therapy HRT is also associated with an increased risk of breast cancer.
The trial was conducted at 55 sites in Germany, Poland and Spain between June and March ; 49 of the participating sites were in Spain. The aim was to determine the value of taxanes for the treatment of axillary node-negative breast cancer in 1, women. Eligible women also had at least one high risk factor for recurrence as defined by the St.
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Skip to Content. Use the menu to see other pages. This section explains the types of treatments that are the standard of care for early-stage and locally advanced breast cancer.
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Please take this quick survey to tell us about what happens after you publish a paper. Pathology Oncology Research. The adjuvant chemotherapy of breast cancer changed in the past two decades.
Patients who have received corneal transplants or cadaver skin or bone transplants are eligible. Obese patients will be treated based on actual body weight. Obese patients treated with full doses based on actual BSA are eligible.
Where can I find treatment guidelines and recommendations for triple-negative breast cancer? New research suggests that even within triple-negative breast cancer, there are many subtypes. Therefore, the best treatment plan is one that your medical team carefully tailors to your unique situation. Generally speaking, treatment for triple-negative breast cancer commonly consists of surgery, chemotherapy given neo-adjuvantly — before surgery — or adjuvantly — after surgeryand radiation.