Breast cancer risk assessment models

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Performance of the Gail and Tyrer-Cuzick breast cancer risk assessment models in women screened in a primary care setting with the FHS-7 questionnaire. The Gail and Tyrer—Cuzick models are the most commonly used, and BC risks assigned by them vary considerably especially concerning familial history. In this study, our aim was to compare the Gail and Tyrer-Cuzick models after initial screening for familial history of cancer in primary care using the FHS-7 questionnaire.

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One of the most well-known is the Gail model, which assesses breast cancer risk based on a series of personal health questions that women and their doctors answer together. The result is a Gail score, which estimates the risk of developing invasive breast cancer in the next 5 years. The result is an estimate of the likelihood a woman will develop invasive breast cancer specifically within 10 years of her current age, as well as over the course of her lifetime.

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This risk assessment tool was developed by scientists at the Wolfson Institute of Preventive Medicine, Queen Mary University of London and is provided for non-commercial research purposes only. No responsibility is accepted for clinical decisions arising from its use. Commercial use requires a license, for further information contact: jtoe cancertechnology.

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Correspondence Address : Dr. It is accounted that 1 in 28 women is likely to develop breast cancer during her lifetime. Developing a risk prediction tool by assessing the prevalence of known risk factors in the community will help public health intervention.

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Skip to Main Content. A not-for-profit organization, IEEE is the world's largest technical professional organization dedicated to advancing technology for the benefit of humanity. Use of this web site signifies your agreement to the terms and conditions.

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Please take this quick survey to tell us about what happens after you publish a paper. Breast Cancer Research. DecemberCite as.

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The Breast Cancer Risk Assessment Tool allows health professionals to estimate a woman's risk of developing invasive breast cancer over the next 5 years and up to age 90 lifetime risk. The tool may underestimate risk in black women with previous biopsies and Hispanic women born outside the United States. Further studies are needed to refine and validate these models.

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View all locations. Breakthroughs Magazine. These tools give approximate, rather than precise, estimates of breast cancer risk based on different combinations of risk factors and different data sets.

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There are two main questions when assessing a woman for interventions to reduce her risks of developing or dying from breast cancer, the answers of which will determine her access: What are her chances of carrying a mutation in a high-risk gene such as BRCA1 or BRCA2? What are her risks of developing breast cancer with or without such a mutation? These risks taken together with the risks and benefits of the intervention will then determine whether an intervention is appropriate. A number of models have been developed for assessing these risks with varying degrees of validation.


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