Soy infant formula and sexual development

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Infants fed soy formula receive high levels of phytoestrogens, in the form of soy isoflavones, during a stage of development at which permanent effects are theoretically possible. However, a paucity of data exists on the long-term effects of infant soy formulas. However, women who had been fed soy formula reported slightly longer duration of menstrual bleeding adjusted mean difference, 0.

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The Canadian Paediatric Society gives permission to print single copies of this document from our website. For permission to reprint or reproduce multiple copies, please see our copyright policy. In the statement, breastfeeding was recognized as the optimal method for feeding infants.

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Soy-based formulas may cause early sexual maturity in baby girls' genitalia, new research suggests. Female infants given the non-dairy formula over cow's milk alternatives or breast milk are significantly more likely to have mature cells in their vaginas, a study found. Previous research suggests soy protein contains high amounts of the oestrogen-like compound genistein, which can alter people's hormone levels and affect their development.

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Russell J. Merritt, Belinda H. Soy protein has been used in infant feeding in the West for nearly y. Soy protein infant formulas have evolved in this interval to become safe and effective alternatives for infants whose nutritional needs are not met with human milk or formulas based on cow's milk.

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Soy-based infant formulas have been consumed in the United States sinceand currently constitute a significant portion of the infant formula market. There are efforts underway to generate genetically modified soybeans that produce therapeutic agents of interest with the intent to deliver those agents in a soy-based infant formula platform. The threefold purpose of this review article is to first discuss the pros and cons of soy-based infant formulas, then present testable hypotheses to discern the suitability of a soy platform for drug delivery in babies, and finally start a discussion to inform public policy on this important area of infant nutrition.

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Although Scientific Societies have stated that there are very few indications for the use of soy-based formula SF in infant nutrition, their utilization rates have been repeatedly found to be higher than expected. It is likely that a significant role in this regard is played by the belief that the use of SF during infancy can reduce the risk of the development of several diseases later in life. Although no definitive data that can substantiate these claims have been collected, many people perceive soy consumption to confer significant health benefits and might also use soy for infant nutrition.

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The following is a guest post by Dr. Kaayla Daniel The Naughty Nutritionist. Thank you Dr.

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Background: Soy-based infant formula contains high levels of isoflavones. These estrogen-like compounds have been shown to induce changes in sexually dimorphic behaviors in animals exposed in early development. Objective: We examined gender-role play behavior in relation to soy-based and non-soy-based infant feeding methods among children in the Avon Longitudinal Study of Parents and Children. Methods: We studied 3, boys and 3, girls.

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It is estimated that an infant exclusively fed soy formula receives the estrogenic equivalent of at least five birth control pills per day. By contrast, almost no phytoestrogens have been detected in dairy-based infant formula or in human milk, even when the mother consumes soy products. A recent study found that babies fed soy-based formula had 13, to 22, times more isflavones in their blood than babies fed milk-based formula.

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Infants who consumed soy-based formula as newborns had differences in some reproductive-system cells and tissues, compared to those who used cow-milk formula or were breastfed, according to a new study. The researchers say the differences, measured in the months after birth, were subtle and not a cause for alarm, but reflect a need to further investigate the long-term effects of exposure to estrogen-like compounds found in soy-based formulas. Stallings is a senior author of a new study published online March 1 in the Journal of Clinical Endocrinology and Metabolism. The first author is Margaret A.


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